Name: Chicken Tetrazzini Casserole Recipe
Prep time: 15 min
Cook time: 45 min
Total time: 1 h
Cuisine: American
Ingredients: 3 cups cooked chicken, chopped or shredded; 1 lb spaghetti; 1 (10.75 oz) can condensed cream of mushroom soup; 1 (10.75 oz) can condensed cream of chicken soup; 1 1/2 cups chicken broth; 1/2 cup heavy cream; 1 1/2 cups sour cream; 2 cups shredded mozzarella cheese, divided; 1 cup shredded cheddar cheese, divided; 1 tsp garlic powder; 1 tsp onion powder; 1/2 tsp Italian seasoning; Salt and black pepper to taste; Olive oil or cooking spray for greasing the dish

Print Recipe· 3.9 from 8 reviews

There is something truly comforting and irresistible about a classic Chicken Tetrazzini Casserole Recipe that brings warmth and joy to any dinner table. Picture tender chicken, twirled spaghetti, and a silky, cheesy sauce baked to golden perfection—all melding into a dish that’s rich, creamy, and so satisfying. This casserole isn’t just a meal; it’s a hug in a dish, perfect for gathering family and friends for a cozy night in or impressing guests with effortless deliciousness.

Ingredients You’ll Need

The image shows an arrangement of ingredients on a white marbled surface. There are nine elements: a bunch of green parsley on the lower left, a white bowl filled with chopped light brown cooked chicken pieces above it, a bundle of uncooked yellow spaghetti pasta positioned to the right of the chicken, and a small white bowl nearby holding a mix of white and black seasonings. Above the chicken and pasta, there are two small clear bowls with shredded cheeses, one with orange shredded cheese and the other with white shredded cheese. Next to the cheeses, a glass container holds a golden-yellow liquid, and beside it, another glass bowl contains white cream. Finally, on the right side, two white bowls contain sauces, one light beige with chunks and another bright yellow creamy texture. All elements are neatly spaced and captured with even lighting. photo taken with an iphone --ar 4:5 --v 7

Gathering the right ingredients for this Chicken Tetrazzini Casserole Recipe is surprisingly simple, yet each component plays a vital role in creating the dish’s luscious texture and deep flavors. From creamy soups to gooey cheeses and flavorful seasoning, these ingredients come together seamlessly for an unforgettable meal.

3 cups cooked chicken: Shredded or chopped, it’s the hearty protein base that makes the dish filling and comforting.
1 lb spaghetti: Cooked al dente to provide the perfect tender bite that holds the creamy sauce beautifully.
1 can condensed cream of mushroom soup (10.75 oz): Adds rich, earthy undertones to the sauce.
1 can condensed cream of chicken soup (10.75 oz): Boosts the savory creaminess essential for that luscious texture.
1 1/2 cups chicken broth: Balances the sauce with lightness and depth of flavor.
1/2 cup heavy cream: Contributes velvety richness for that indulgent mouthfeel.
1 1/2 cups sour cream: Adds tang and smooth consistency, brightening the sauce.
2 cups shredded mozzarella cheese: Melts beautifully, creating gooey, stringy texture on top and inside.
1 cup shredded cheddar cheese: Brings an extra layer of sharpness and color contrast.
1 tsp garlic powder: Infuses subtle savory aroma and depth.
1 tsp onion powder: Adds a gentle sweetness to the flavor profile.
Salt and black pepper to taste: Essential for seasoning and bringing all flavors into harmony.
1/2 tsp Italian seasoning: Offers herbaceous notes that lighten and refresh the creamy richness.

How to Make Chicken Tetrazzini Casserole Recipe

Step 1: Prepare Your Oven and Dish

Begin by preheating your oven to 350°F and greasing a 9×13 casserole dish with olive oil or cooking spray. This simple step keeps your cheesy masterpiece from sticking and ensures an easy serving experience once baked.

Step 2: Cook the Spaghetti

Bring a large pot of salted water to a boil, then add the spaghetti. Cook for about 12 minutes or until al dente—the ideal texture for absorbing the sauce without becoming mushy. Before draining, save a cup of that starchy pasta water; it’s a secret weapon for adjusting your sauce’s consistency later! Rinse the pasta with cold water to stop the cooking process and keep the strands separate.

Step 3: Mix the Creamy Sauce

In a large bowl, whisk together the cream of mushroom soup, cream of chicken soup, chicken broth, heavy cream, and sour cream. This combo forms the decadent base sauce that wraps around every noodle and morsel of chicken in silky perfection.

Step 4: Season and Add Chicken

Sprinkle in garlic powder, onion powder, black pepper, Italian seasoning, and salt to taste, mixing thoroughly. Then fold in your chopped or shredded chicken, ensuring every piece gets bathed in the flavorful sauce.

Step 5: Combine Pasta and Sauce

Stir your cooked spaghetti into the creamy mixture until it’s evenly coated. If the mixture feels a little dry, gently stir in the reserved pasta water a bit at a time until it reaches a luscious, saucy consistency that clings to the noodles.

Step 6: Layer and Add Cheese

Transfer half of your chicken pasta mixture into the prepared casserole dish. Sprinkle 1 cup of shredded mozzarella and ½ cup of shredded cheddar cheese evenly on top to create a cheesy molten layer. Add the remaining chicken pasta over the cheese, then crown the dish with the remaining mozzarella and cheddar cheese. This layering promises gooey, cheesy pockets throughout the casserole.

Step 7: Bake Until Bubbling and Golden

Pop your dish into the preheated oven and bake for 35 to 45 minutes. Watch for a bubbling sauce and golden cheese crust forming on top—that’s your sign that this chicken tetrazzini casserole is ready to be devoured.

Step 8: Let It Rest

Before digging in, let the casserole rest for about 5 minutes. This brief pause allows the flavors to settle and the sauce to thicken slightly, making serving a clean and delicious breeze.

How to Serve Chicken Tetrazzini Casserole Recipe

Garnishes

Fresh herbs like parsley or chives make perfect garnishes for this Chicken Tetrazzini Casserole Recipe. They add a burst of color and a hint of brightness that complements the creamy, cheesy richness wonderfully.

Side Dishes

To round out the meal, serve this casserole alongside crisp green beans, a fresh mixed green salad, or warm garlic bread. Each side offers contrasting textures and flavors that balance the indulgent main dish beautifully.

Creative Ways to Present

For a fun presentation, try serving individual portions in small ramekins or hollowed-out bread bowls. It highlights the cozy, homestyle charm of Chicken Tetrazzini Casserole Recipe and adds a touch of personality to your dinner table.

Make Ahead and Storage

Storing Leftovers

Any leftover chicken tetrazzini casserole can be stored in an airtight container in the refrigerator for up to 3 days. Cover it tightly to keep the sauce from drying out and retain all that creamy goodness.

Freezing

This casserole freezes beautifully. Simply wrap it tightly with plastic wrap and foil or store in a freezer-safe container. It can be frozen for up to 2 months, making it a fantastic make-ahead meal for busy days.

Reheating

To reheat, thaw overnight in the fridge if frozen. Warm individual portions in the microwave or reheat the entire casserole in a 350°F oven, covered with foil to prevent drying, for about 20-25 minutes until heated through and bubbly.

FAQs

Can I use a different type of pasta for this Chicken Tetrazzini Casserole Recipe?

Absolutely! While spaghetti is classic, other long pasta like linguine or even short pasta such as penne or fusilli work well. Just adjust cooking times accordingly and remember that the texture may slightly change.

Is it okay to use rotisserie chicken instead of cooked homemade chicken?

Yes, using rotisserie chicken is an excellent shortcut that adds delicious flavor and saves prep time. Just shred or chop it before adding to your sauce mixture.

Can I make this casserole gluten-free?

Definitely. Use gluten-free pasta and ensure your cream soups are gluten-free or substitute with homemade sauce versions. This way, you keep all the comfort without worry.

What can I add to make this Chicken Tetrazzini Casserole Recipe healthier?

Try adding steamed vegetables like mushrooms, peas, or spinach for extra nutrients and flavor. Opting for reduced-fat cheeses and skipping heavy cream for milk options can also lighten the dish.

Can I prepare the casserole a day ahead before baking?

Yes, you can assemble the casserole and refrigerate it overnight. When ready to serve, just add a few extra minutes to the baking time to ensure it’s heated through completely.

Final Thoughts

Making the Chicken Tetrazzini Casserole Recipe is like crafting a tasty memory that you’ll want to revisit again and again. It’s rich and creamy, cheesy and comforting—all the best qualities rolled into one gorgeous dish. Whether it’s a family dinner or a special occasion, this casserole promises warmth, satisfaction, and happy smiles all around. Give it a try today and watch it quickly become one of your all-time favorites!